Brand

Perricone MD

Perricone MD was founded in 1997 by Dr. Nicholas Perricone, a board-certified dermatologist and bestselling author who popularized the 'inflammation theory of aging' -- the idea that chronic, low-level inflammation is the primary driver of visible skin aging. His books, including 'The Wrinkle Cure' and 'The Perricone Prescription,' became New York Times bestsellers and made him one of the most famous dermatologists in America. The brand's formulations center on DMAE (dimethylaminoethanol) for firming and alpha lipoic acid as an antioxidant. With 6 products across 4 categories averaging 83/100 at the premium tier, Perricone MD delivers strong anti-aging formulations grounded in its founder's inflammation research.

PremiumLuxury Dermatologist Recommended Est. 1997 San Francisco, California, USA THG (The Hut Group, acquired 2020)

6 Products

38 Evaluations

83 Avg Score

4 Categories

Best Perricone MD product by condition:

Dry 82 Oily 91 Combo 89 Acne 93 Sensitive 86 Aging 92

Brand Philosophy

Perricone MD targets inflammaging -- the chronic inflammation that accelerates visible aging. Every formulation aims to reduce inflammatory triggers while delivering antioxidant and firming actives. The brand combines dermatological science with a nutritional approach to skin health.

Who It's For

Anti-aging consumers interested in the inflammation theory of aging who want dermatologist-developed products with potent antioxidant and firming actives.

Known For

Anti-inflammaging approach
Cold Plasma+ line
DMAE firming technology
Bestselling dermatology books
Alpha lipoic acid formulations

Signature Ingredients

DMAE
Alpha Lipoic Acid
Vitamin C Ester
Neuropeptides
Phospholipids

Perricone MD at a Glance

Strongest Categories

Perricone MD performs best in: Acne Treatment (2 products, avg 88/100); Anti-Aging Treatment (2 products, avg 82/100); Brightening Treatment (1 product, avg 80/100).

Best Conditions Served

Across all products, Perricone MD scores highest for: Oily Skin (avg 91/100); Aging/Mature Skin (avg 88/100); Combination Skin (avg 88/100). If your primary concern is one of these conditions, Perricone MD products are particularly worth considering.

Certifications

Common certifications include Cruelty-Free, Fragrance-Free, Paraben-Free, Sulfate-Free.

Best Perricone MD by Skin Condition

The highest-scoring Perricone MD product for each condition we evaluate.

Dry/Dehydrated

All Perricone MD Products (6)

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Acne Treatment & Night Moisturizer High

Acne Treatment

Perricone MD Acne Relief Retinol Treatment & Moisturizer

Perricone MD Acne Relief Calming & Soothing Clay Mask

Multi-Tasking Anti-Aging Serum High

Anti-Aging Treatment

Perricone MD Cold Plasma Plus+ Advanced Serum Concentrate

Acne Treatment Cleanser High

Cleanser

Perricone MD Acne Relief Gentle & Soothing Cleanser

Anti-Aging Serum High

Anti-Aging Treatment

Perricone MD High Potency Growth Factor Firming & Lifting Serum

Brightening Treatment

Perricone MD Vitamin C Ester Brightening Serum

Frequently Asked Questions about Perricone MD

What is the best Perricone MD product?

Based on our scoring, Perricone MD Acne Relief Retinol Treatment & Moisturizer is the highest-rated Perricone MD product with a score of 93/100 for acne-prone skin. Exceptional acne treatment. Triple-action formula targets oil, bacteria, and inflammation without overdrying.

Is Perricone MD worth the price?

Perricone MD products are positioned at the premium tier with an average score of 83/100 across 6 evaluated products. Check individual product scores to determine whether specific products justify the investment for your skin concern.

What skin type is Perricone MD best for?

Perricone MD scores highest for oily skin, with an average score of 91/100 across relevant products. They also perform well for aging/mature skin and combination skin. Check condition-specific scores for the product you are considering.

Every Perricone MD product above has been scored individually for each relevant skin condition. Click any product to see its full evaluation, ingredient analysis, and usage guidance for your specific concern.