Brand

Biossance

Biossance was launched in 2016 by Amyris, a biotechnology company originally founded in 2003 to produce anti-malarial drugs using synthetic biology. Amyris developed a sustainable method of producing squalane from sugarcane fermentation rather than traditional shark liver extraction, and Biossance was created to bring this technology to clean beauty. Their sugarcane-derived squalane is the foundation of every product. The brand represents genuine biotech innovation applied to clean skincare -- not marketing-driven clean beauty but a brand born from actual biotechnology. With 7 products across 6 categories averaging 84/100, Biossance delivers strong, clean formulations anchored by their uniquely sourced squalane.

Premium Dermatologist Recommended Est. 2016 Emeryville, California, USA Amyris

7 Products

54 Evaluations

84 Avg Score

6 Categories

Best Biossance product by condition:

Dry 96 Oily 89 Combo 88 Acne 91 Sensitive 92 Aging 92

Brand Philosophy

Biossance applies biotechnology to create sustainable, effective skincare. The brand's core innovation is sugarcane-derived squalane that eliminates shark-derived squalane from the supply chain. Every formulation combines this sustainable hero ingredient with proven actives in clean, cruelty-free formulations.

Who It's For

Clean beauty consumers who want sustainability backed by real biotechnology rather than marketing. Excellent for dry, sensitive, and normal skin types.

Known For

Sugarcane-derived squalane
Biotech origins
Squalane + Vitamin C Rose Oil
Shark-free squalane pioneer
Clean beauty with genuine science

Signature Ingredients

Sugarcane Squalane
Vitamin C
Retinol
Hyaluronic Acid
Rose Oil

Biossance at a Glance

Strongest Categories

Biossance performs best in: Brightening Treatment (1 product, avg 88/100); Exfoliant (1 product, avg 86/100); Anti-Aging Treatment (1 product, avg 85/100).

Best Conditions Served

Across all products, Biossance scores highest for: Aging/Mature Skin (avg 87/100); Dry/Dehydrated Skin (avg 86/100); Sensitive Skin (avg 85/100). If your primary concern is one of these conditions, Biossance products are particularly worth considering.

Certifications

Common certifications include Vegan, Cruelty-Free, EWG Verified, Clean at Sephora, Fragrance-Free, Non-Comedogenic.

Best Biossance by Skin Condition

The highest-scoring Biossance product for each condition we evaluate.

Dry/Dehydrated

All Biossance Products (7)

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Face Cream High

Moisturizer

Biossance Squalane + Omega Repair Cream

Lactic Acid Night Serum High

Exfoliant

Biossance Squalane + 10% Lactic Acid Resurfacing Night Serum

Brightening Facial Oil High

Brightening Treatment

Biossance Squalane + Vitamin C Rose Oil

Biossance Squalane + Probiotic Gel Moisturizer

Anti-Aging Serum (Bakuchiol-Based) High

Anti-Aging Treatment

Biossance Squalane + Phyto-Retinol Serum

Biossance Squalane + Amino Aloe Gentle Cleanser

Biossance Squalane + Marine Algae Eye Cream

Frequently Asked Questions about Biossance

What is the best Biossance product?

Based on our scoring, Biossance Squalane + Omega Repair Cream is the highest-rated Biossance product with a score of 96/100 for dry/dehydrated skin. Best-in-class barrier repair cream. Biomimetic lipids restore chronic dryness at cellular level.

Is Biossance worth the price?

Biossance products are positioned at the premium tier with an average score of 84/100 across 7 evaluated products. Check individual product scores to determine whether specific products justify the investment for your skin concern.

What skin type is Biossance best for?

Biossance scores highest for aging/mature skin, with an average score of 87/100 across relevant products. They also perform well for dry/dehydrated skin and sensitive skin. Check condition-specific scores for the product you are considering.

Every Biossance product above has been scored individually for each relevant skin condition. Click any product to see its full evaluation, ingredient analysis, and usage guidance for your specific concern.